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Wednesday, November 19, 2025

Is Excessive Dose Supplementation Protected?


Iodine is without doubt one of the important minerals that we have to be wholesome. Everyone seems to be taught that iodine is required for the thyroid, and so they’re proper, however iodine can achieve this rather more.

Docs and well being professionals are simply advised that it is wanted for the thyroid and also you should not take any extra. They’re principally afraid of individuals getting extra, for it would trigger hyperthyroidism. Then again, there’s different individuals who say you need to take much more. And so there’s a whole lot of conflicting info.

On this publish, we’ll dive into the advisable dietary allowance (RDA) for iodine, discuss how a lot the physique might really profit from, and focus on what occurs to your thyroid whenever you take excessive doses of it, together with the Wolf-Chaikoff impact, then attain a balanced conclusion on the security of iodine. Is it secure for you? That is what you actually wish to know. I will aid you reply that query.

Understanding the RDA for Iodine: Why So Low?

The RDA for iodine is about at 150 micrograms per day for many adults. It’s kind of increased for pregnant girls and for breastfeeding girls as properly. The RDA is principally set to forestall iodine deficiency, which might result in hypothyroidism.

The traditional case of hypothyroidism occurs when your thyroid is not producing sufficient hormones, usually on account of not having sufficient iodine within the physique. Because of low ranges of iodine, the thyroid gland really will get bigger, attempting to extract any little little bit of iodine it could possibly get its receptors on to make thyroid hormone. We name the enlarged thyroid a goiter. It was rather more frequent, particularly in the midst of the continent the place the iodine ranges are very low within the soil. And now with the iodized salt, you do not see that a lot in any respect.

How did they ever work out how a lot iodine you wanted? Effectively, it got here from research within the 50s and 60s that checked out thyroid iodine accumulation and turnover. Researchers decided that intakes beneath 10 to twenty micrograms a day would trigger goiter and hypothyroidism. In order that they moved as much as 150 mcg as a stage that was ample to take care of regular thyroid operate for nearly all people, with a security issue inbuilt.

So, the RDA was actually set to keep away from deficiency and to offer sufficient iodine for correct thyroid operate. The main target was on thyroid well being, guaranteeing you made sufficient thyroid hormones like T3 and T4, which regulate metabolism, power, and general bodily features, that are very essential features, really.

However iodine is used for lots of different glands moreover the thyroid. That is the following matter we have to cowl right here.

How A lot Iodine Does the Physique Actually Want?

Regardless that the RDA is 150 micrograms, there’s proof from a whole lot of totally different investigations that recommend the physique may benefit from increased quantities—milligram quantities, doubtlessly within the vary of 1 to three milligrams per day (that is 1,000 to three,000 micrograms a day), so at the very least 10 occasions as a lot because the RDA.

A few of this proof comes from observations and populations just like the Japanese individuals, the place they eat a whole lot of seaweed and seafood and have low charges of thyroid issues.

Proponents resembling David Derry, PhD, MD, and David Brownstein, MD, argue that increased doses of iodine assist not simply the thyroid, however assist different glands and tissues within the physique as properly. Dr. David Derry, particularly, in his guide Breast Most cancers and Iodine, reveals how iodine will be very useful for this quite common illness, breast most cancers.

Dr. Brownstein offers with an entire vary of ailments, together with thyroid ailments resembling Graves’ illness and Hashimoto’s illness, and reveals how increased ranges of iodine might help even these circumstances of thyroid dysfunction.

The case towards increased doses of iodine

Whereas there are a number of proponents of upper ranges of iodine for the physique, mainstream well being organizations nonetheless keep that there isn’t any robust proof for intakes above the RDA that would supply further advantages for most individuals. They nonetheless consider iodine for the thyroid as the first and actually solely operate that we have to fear about for iodine. There isn’t any profit to the physique exterior of the thyroid for iodine so far as mainstream medication is worried. And they might go as far as to say that taking increased ranges of iodine is definitely harmful. They do not see any profit, simply threat of thyroid maladaption at increased doses. In order that they advise towards it.

In fact, you might be allowed to do your individual analysis and you need to. Should you’re seeking to optimize your physique’s features past simply iodine deficiency prevention, you may wish to discover increased doses of iodine.

The case for extra iodine

Based on an up to date 2016 iodine analysis abstract that I’ve put collectively, whereas the thyroid requires solely microgram quantities of iodine, the remainder of the physique advantages from lots of of micrograms and even milligrams—doubtlessly as much as 100 occasions the RDA—to assist general well being. Excessive-dose iodine aids the immune system in combating infections, balances estrogen for reproductive well being (together with breasts, ovaries, endometrium, and prostate), normalizes ldl cholesterol and blood strain, improves glucose metabolism for higher diabetes administration, helps central nervous system growth, and should improve bone well being, lung operate, and pores and skin integrity. It additionally helps detoxify heavy metals and bromide from the physique. For common well being upkeep, 1-3 mg per day is recommended, whereas these with suboptimal organ operate could safely use as much as 50 mg every day, with thyroid monitoring advisable for intakes over 10 mg regularly. Yow will discover the iodine analysis abstract right here.

If you’d like a fast have a look at the proof for iodine’s advantages past the thyroid, together with power, immunity, hormones, and extra, try this text: Iodine Advantages Past the Thyroid: Power, Immunity, Hormones and Extra.

What Occurs When You Take Excessive Doses? The Wolf-Chaikoff Impact Defined

One of many fundamental considerations with high-dose iodine is what is known as the Wolf-Chaikoff impact. This misunderstood mechanism simply appears to be a pure protecting mechanism for the thyroid.

When there is a sudden inflow of iodine, say from a complement or from a distinction media or some medical intervention, the thyroid briefly shuts down hormone manufacturing to keep away from overproducing T3 and T4 primarily based on the same old low iodine availability. The thyroid often has a lot of iodine receptors on its floor, however when there’s an enormous flood of iodine coming in, it has to downregulate the manufacturing of thyroid hormone so you aren’t getting manner an excessive amount of of it being produced.

This sudden response often solely lasts a number of days. After that, the thyroid gland adjusts to the now normal stage of iodine floating round within the blood and it reduces the variety of iodine trapping receptors on its floor. Drawback over. That is how the thyroid gland is meant to usually work. The one time there’s hassle is when it would not work because it must work.

We are able to consider this because the thyroid simply recalibrating to a brand new abundance of iodine. It is simply a part of regular physiology. It often resolves by itself in a course of the medical doctors name, “escape” from the “Wolf-Chaikoff” impact.

In actuality, it is not a giant deal. Hormone manufacturing resumes usually. Nonetheless, in a number of uncommon circumstances, if the physique would not get well regular thyroid hormone manufacturing, it might result in a hypothyroid state. In order that’s one of many risks of taking a whole lot of iodine.

One of many key factors in a 2013 evaluate on iodine referred to as “Penalties of Extra Iodine” by Leung and Braverman was that iodine is “typically properly tolerated in most individuals.”

On the flip aspect, those that have autonomous thyroid nodules (that are unbiased of regular regulatory controls) may expertise hypothyroidism as its nodules might begin producing giant quantities of thyroid hormone, exterior the conventional checks and balances within the thyroid gland.

This is not quite common in any respect, however if you’re an individual with a historical past of thyroid points, you may wish to get it checked out earlier than beginning excessive doses of iodine. That is all. For many wholesome individuals, this is not something to fret about.

So, Is Excessive-Dose Iodine Protected?

In conclusion, is high-dose iodine all threat and no profit? No. Mainstream medication has it improper. There’s a whole lot of potential profit and little or no threat. That is the right manner of taking a look at this.

In a number of vulnerable individuals, iodine might result in hypothyroidism, or, if in case you have unbiased nodules, to hyperthyroidism. However most individuals tolerate as much as a milligram or extra with out points in any respect.

At Hallelujah Weight loss program, we have been promoting iodine dietary supplements for greater than 20 years, and we’ve not encountered stories of unfavourable reactions, notably when utilizing nascent iodine.

When you have thyroid points, speak to a healthcare skilled that is conversant in high-dose iodine. They might help you navigate your explicit circumstances.

In the end, excessive dose iodine is not simply secure, it could possibly be very useful for you in supporting the well being of your entire physique. Begin sluggish, monitor how your physique responds, and work as much as a better dose. Many individuals have already discovered that it’s value the additional effort.

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